Here are some special cases that are not covered in the safety section when talking about Lorazepam.
- Senior population and children under the age of fourteen are a problematic group when talking about Lorazepam because very few studies have been conducted on their usage. However, it has been known to for treatment of momentary seizures. Dosages given need to be considered from person to person and cannot be generalized, additionally so in the senior patients and patients who are debilitated since the risk of overdose is somewhat greater. Prolonged usage of Lorazepam can cause some lowering of cognitive functions, especially with the senior population, and those effects might not be revocable after the treatment is stopped. Older patients usually need more time to fully digest and run through their metabolism, when compared to younger patients, and are more susceptible to the paradoxical effects of Lorazepam. One more thing to be considered is that older patients have a tendency to take more than one medication at the same time, which always opens a risk of drug interaction with Lorazepam. In addition, one of the possible side effects of Lorazepam is possible momentary loss of muscle control leading to possible falls, which can cause a lot more damage in seniors than in regular patients. This all being said, starting doses for the senior population is usually half of that given to younger patients. Lorazepam also might take longer than usual to completely clear from the system of elder patients, leading to the increased chance of appearance of any adverse effects and even in some cases enhanced overall effect. Lorazepam, like similar benzo-drugs can lead to problems with bodies balance and ability to stand still, after waking up. Many fallings and fracturing of the hips are reported, and should be monitored regularly in cases when this combined with alcohol can lead to additional increased problems.
- In case of patients with renal or liver problems Lorazepam can be an option, because it is considered a much’ better option than most benzos. Since it does not require oxidation in the liver, it can safely be given to patients with liver problems, without the risk of it not working, or worsening the state of the liver. It is also true for kidney diseases and disorders; they do not affect Lorazepam blood levels in any way.
- As mentioned before there is a risk of abuse of Lorazepam and should be extremely careful when giving to someone who has a history of drug or alcohol abuse.
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In case of using Lorazepam before an operation, the constant form that the patient is required to sign can be disputed if it was signed after receiving a dose of Lorazepam. In addition, the dosage should be monitored to prevent any possible abuse while the operation and recovery periods. Since Lorazepam lowers your ability to process decisions and somewhat prolonged sedative effects, it is best used for patients while he is in the medical facility. Patients who have received a dose of Lorazepam for premedication should not be allowed to leave the hospital unless someone is willing to look after them for twenty-four hours.
In case of using Lorazepam before an operation, the constant form that the patient is required to sign can be disputed if it was signed after receiving a dose of Lorazepam. In addition, the dosage should be monitored to prevent any possible abuse while the operation and recovery periods. Since Lorazepam lowers your ability to process decisions and somewhat prolonged sedative effects, it is best used for patients while he is in the medical facility. Patients who have received a dose of Lorazepam for premedication should not be allowed to leave the hospital unless someone is willing to look after them for twenty-four hours.
